January 27, 2025
December 20, 2019
Therapeutic Strategies to Induce Dormancy in Disse...
Metastasis is the main cause of melanoma death. Current treatments mostly fail to cure metastasis. It is of common knowledge that disseminated cancer cells (DCCs) are the...
December 20, 2019
Augmenting Melanoma Response to Immunotherapy via ...
Cancer immunotherapy (CI) drugs activate our own immune system to directly kill cancer cells. These drugs have revolutionized how we treat many cancers including melanoma....
December 20, 2019
Modulating p53 Transcriptional Activity to Reduce ...
Successful management of melanoma will require eliminating both the primary cancer as well as its spread. The survival of melanoma patients reduces significantly if the ...
December 20, 2019
Pharmacological Targeting of Estrogen Receptor to ...
The development of new classes of drugs which target pathways required for melanoma growth and approaches to increase tumor immunogenicity (Immune Checkpoint Blockade (ICB)...
December 20, 2019
Characterizing the Role of the Hippo Pathway Durin...
The Hippo pathway in cancer, mediated by YAP1, has been implicated in therapy resistance and aggressive tumor behavior in melanomas treated with targeted therapies. However...
