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Melanoma is a lethal form of skin cancer because it has a high propensity to metastasize, especially to the brain (often causing death). Compounding this problem is the obs...
Description: Mucosal melanoma (MM) is a rare form of melanoma with poor survival outcomes. Data on treatment for MM is limited to results from studies on cutaneous melanoma...
Description: For patients with melanoma, timely diagnosis and prompt treatment are important for optimal outcomes, but some groups of patients may face barriers to accessin...
Description: Pigmentation, or the coloring of the skin, hair and mucous membranes, has been shown to influence melanoma risk. Most, if not all traits and diseases, have a g...
Description: Findings from this grant will shed light on 1) how stemness is sustained by modulating PI3Kδ signaling in T cells using FDA-approved drugs and 2) how transcri...
Description: While immunotherapy treatment has radically improved the outcomes of patients with advanced melanoma, around half of patients have no response. This is in part...
Description: According to the latest published statistics by the NIH, there are almost half a million individuals who are cancer survivors after having been diagnosed with ...
Description: While several medications, immune stimulating agents, and radiation therapies have been developed and used for the treatment of melanoma, the treatment options...
Description: Hybrid cells, in circulation and in the tumor are reprogrammed cancer cells displaying immune cell mimicry—insights into their impact on tumor progression, i...
Description: Background: Racial inequities in melanoma survival have been documented in the literature. The largest Black-white difference in overall cancer survival is for...
Description: Immunotherapy has been shown to be effective in treating melanoma, even at an early stage of disease. Patients with Stage II melanoma are now able to receive a...
