January 27, 2025
Blogs
3 Minute Read
FEATURED | May 1, 2025
Why I’m Getting Naked for Skin Health
Guest blog post by Ian Michael Crumm, Celebrity Esthetician, Podcast Host, Key Opinion Leader, Melanoma Advocate and 2025 #GetNaked Spokesperson: Some moments stick with yo...
December 23, 2019
Targeting Melanoma Developmental Programs to Overc...
Description: Melanoma is the most aggressive form of skin cancer. Although progress has been made for advanced melanoma patients with 13 new FDA-approved therapies since 20...
December 20, 2019
Therapeutic Strategies to Induce Dormancy in Disse...
Metastasis is the main cause of melanoma death. Current treatments mostly fail to cure metastasis. It is of common knowledge that disseminated cancer cells (DCCs) are the...
December 20, 2019
Role of PRAME in Epigenetic Reprogramming and Chro...
UM has a propensity to undergo early micrometastasis prior to treatment of the primary tumor, with later emergence of overt metastatic disease. Unfortunately, there has b...
December 20, 2019
Augmenting Melanoma Response to Immunotherapy via ...
Cancer immunotherapy (CI) drugs activate our own immune system to directly kill cancer cells. These drugs have revolutionized how we treat many cancers including melanoma....
December 20, 2019
Modulating p53 Transcriptional Activity to Reduce ...
Successful management of melanoma will require eliminating both the primary cancer as well as its spread. The survival of melanoma patients reduces significantly if the ...
December 20, 2019
Pharmacological Targeting of Estrogen Receptor to ...
The development of new classes of drugs which target pathways required for melanoma growth and approaches to increase tumor immunogenicity (Immune Checkpoint Blockade (ICB)...
December 20, 2019
Cellular and Genomic Landscape of Uveal Melanoma a...
Uveal melanoma (UM) is a highly aggressive eye cancer that leads to metastatic death in up to half of patients, with no measurable improvement in survival over the past hal...
December 20, 2019
The Development and Characterization of Cellular M...
Melanoma is the most aggressive form of skin cancer. Although progress has been made for advanced melanoma patients with 13 new FDA-approved therapies since 2011, resistanc...
December 20, 2019
Characterizing the Role of the Hippo Pathway Durin...
The Hippo pathway in cancer, mediated by YAP1, has been implicated in therapy resistance and aggressive tumor behavior in melanomas treated with targeted therapies. However...
